Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750629 | 0.90 | TSPO (0.45) | TSPO | |
| SCHEMBL7497068 | 0.86 | DHODH (0.46) | TSPO | |
| SCHEMBL7497415 | 0.84 | KDM4E (0.41) | TSPO | |
| SCHEMBL7492350 | 0.82 | POLB (0.42) | — | |
| SCHEMBL7499843 | 0.82 | CYP1A2 (0.41) | TSPO | |
| SCHEMBL7750405 | 0.79 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL7489787 | 0.78 | TSPO (0.52) | TSPO | |
| SCHEMBL7497799 | 0.78 | TSPO (0.71) | TSPO | |
| SCHEMBL7497413 | 0.77 | MAPT (0.42) | TSPO | |
| SCHEMBL600372 | 0.76 | TSPO (0.78) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000063-B1 | 4-OXO-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-b]INDOLE-1-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI SYNTHELABO (FR) | 2002-10-23 | — | — | EP | disclosed |
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |