Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420000 | 1.00 | NPC1 (0.56) | NPC1MEN1KMT2APIN1ALDH1A1 | |
| Pentachlorophenol SCHEMBL10449710 | 0.88 | MEN1 (0.46) | NPC1MEN1KMT2APIN1ALDH1A1 | |
| SCHEMBL2911173 | 0.85 | ALDH1A1 (0.51) | NPC1MEN1KMT2APIN1ALDH1A1 | |
| SCHEMBL20350872 | 0.83 | KDM4E (0.49) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1380026 | 0.83 | KMT2A (0.45) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6618828 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1MAPTLMNATSHR | |
| SCHEMBL2098734 | 0.81 | NPC1 (0.59) | NPC1MEN1KMT2APIN1ALDH1A1 | |
| SCHEMBL27715083 | 0.81 | NPC1 (0.59) | NPC1MEN1KMT2APIN1ALDH1A1 | |
| SCHEMBL28226195 | 0.81 | NPC1 (0.59) | NPC1MEN1KMT2APIN1ALDH1A1 | |
| SCHEMBL13724641 | 0.81 | HDAC3 (0.50) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447551-A | Method for preparing blonanserin | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-12378200-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ORSOBIO, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| CN-120136839-A | Method for synthesizing polysubstituted thiophene compounds | 南京理工大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-120136839-A | Method for synthesizing polysubstituted thiophene compounds | 南京理工大学 | 2025-06-13 | — | — | CN | disclosed |
| US-20250145572-A1 | Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) Inhibitors | ORSOBIO INC (US) | 2025-05-08 | — | — | US | disclosed |
| EP-3778547-B1 | FLUORINATED ORGANIC COMPOUND PRODUCTION METHOD | DAIKIN IND LTD (JP) | 2024-07-31 | — | — | EP | disclosed |
| CN-112004793-B | Process for producing fluorinated organic compound | 大金工业株式会社 | 2024-02-27 | — | — | CN | disclosed |
| US-20240059657-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | OrsoBio Inc. | 2024-02-22 | — | — | US | disclosed |
| EP-3778548-B1 | FLUORINATED ORGANIC COMPOUND PRODUCTION METHOD | DAIKIN IND LTD (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-11827594-B2 | Fluorinated organic compound production method | DAIKIN INDUSTRIES, LTD. (JP) | 2023-11-28 | — | — | US | disclosed |
| CN-1219172-A | Novel benzo-1, 3-dioxolyl-and benzofuranyl-substituted pyrrolidine derivatives as endothelin antagonists | ABBOTT LAB CO (US) | 1999-06-09 | — | — | CN | disclosed |
| EP-0438209-B1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL IND LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| CN-1081672-A | carboxylic acid derivative and preparation method thereof | NIPPON SHINYAKU CO LTD (JP) | 1994-02-09 | — | — | CN | disclosed |
| US-5116404-A | URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0438209-A1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-4795812-A | ANTITUMOR | THE UPJOHN COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0210228-A1 | 4-SUBSTITUTED-6-ARYL PYRIMIDINE COMPOUNDS | THE UPJOHN COMPANY (US) | 1987-02-04 | — | — | EP | disclosed |
| WO-1986004583-A1 | 4-SUBSTITUTED-6-ARYL PYRIMIDINE COMPOUNDS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |
| US-4552694-A | ANTISEPTICS, INSECTICIDES | DAIKIN INDUSTRIES LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| EP-0133322-A1 | Fluorinated benzodiazepins | DAIKIN INDUSTRIES, LIMITED (JP) | 1985-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378200-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ALDH7A1, ACMSD, AMD1 | NPC1 2098/4885MEN1 1478/4885KMT2A 1309/4885 |
| US-20250145572-A1 | Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) Inhibitors | ACMSD, ALDH7A1, ALAD | NPC1 2371/4885MEN1 1560/4885KMT2A 978/4885 |
| US-20240059657-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | ALDH7A1, ACMSD, AMD1 | NPC1 2098/4885MEN1 1478/4885KMT2A 1309/4885 |
| US-11827594-B2 | Fluorinated organic compound production method | AFF2, TPO, AFF1 | NPC1 836/4885MEN1 274/4885KMT2A 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.