Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494152 | 0.88 | TSHR (0.39) | TSHRALDH1A1PTAFRGALR3RAB9A | |
| Hydrochloric Acid SCHEMBL7503056 | 0.71 | — | — | |
| SCHEMBL23909527 | 0.67 | CA1 (0.41) | ALDH1A1 | |
| SCHEMBL11446278 | 0.65 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL1340299 | 0.63 | ALDH1A1 (0.48) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28252892 | 0.62 | ALDH1A1 (0.47) | TSHRALDH1A1 | |
| SCHEMBL23909606 | 0.62 | CA1 (0.42) | ALDH1A1 | |
| SCHEMBL26932757 | 0.61 | L3MBTL1 (0.40) | — | |
| SCHEMBL18030917 | 0.60 | IMPDH2 (0.46) | TSHRALDH1A1 | |
| SCHEMBL21076112 | 0.60 | AR (0.38) | TSHRALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |