Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749993 | 0.91 | LPAR1 (0.39) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL745530 | 0.89 | HDAC1 (0.41) | TMEM97SIGMAR1MEN1KMT2ANPC1 | |
| SCHEMBL748197 | 0.89 | SRC (0.36) | LMNAALDH1A1KCNH2TMEM97SIGMAR1 | |
| SCHEMBL750133 | 0.89 | SRC (0.36) | LMNAKCNH2SIGMAR1MEN1KMT2A | |
| SCHEMBL750950 | 0.89 | SRC (0.36) | LMNAALDH1A1TMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL750906 | 0.88 | TP53 (0.39) | LMNASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL747722 | 0.88 | ESRRG (0.41) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL751875 | 0.88 | SRC (0.36) | LMNAALDH1A1TMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL746652 | 0.88 | F2 (0.44) | LMNAALDH1A1TMEM97SMN1; SMN2GAA | |
| SCHEMBL751065 | 0.87 | SRC (0.38) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |