Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745530 | 0.91 | HDAC1 (0.41) | SRCSIGMAR1HDAC1HDAC6SLC13A5 | |
| SCHEMBL749993 | 0.89 | LPAR1 (0.39) | SRCHDAC1HDAC6SLC13A5MEN1 | |
| SCHEMBL749647 | 0.89 | LMNA (0.39) | SIGMAR1MEN1KMT2ALMNAKCNH2 | |
| SCHEMBL750950 | 0.89 | SRC (0.36) | SRCSIGMAR1HDAC1HDAC6SLC13A5 | |
| SCHEMBL748197 | 0.89 | SRC (0.36) | SRCSIGMAR1HDAC1HDAC6SLC13A5 | |
| SCHEMBL747722 | 0.88 | ESRRG (0.41) | SRCHDAC1HDAC6SLC13A5BCHE | |
| SCHEMBL750906 | 0.88 | TP53 (0.39) | SRCHDAC1HDAC6SLC13A5MEN1 | |
| Hydrochloric Acid SCHEMBL751875 | 0.88 | SRC (0.36) | SRCSIGMAR1HDAC1HDAC6SLC13A5 | |
| SCHEMBL751838 | 0.88 | ACHE (0.43) | SRCSIGMAR1HDAC1HDAC6SLC13A5 | |
| SCHEMBL751065 | 0.87 | SRC (0.38) | SRCHDAC1HDAC6SLC13A5BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |