Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 7/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 4/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745530 | 0.94 | HDAC1 (0.41) | ESRRGHDAC1HDAC6SRCSLC13A5 | |
| SCHEMBL750906 | 0.93 | TP53 (0.39) | ESRRGHDAC1HDAC6SRCSLC13A5 | |
| SCHEMBL749993 | 0.92 | LPAR1 (0.39) | HDAC1HDAC6SRCSLC13A5HIF1A | |
| SCHEMBL751065 | 0.92 | SRC (0.38) | ESRRGHDAC1HDAC6SRCSLC13A5 | |
| SCHEMBL746738 | 0.89 | SRC (0.36) | ESRRGHDAC1HDAC6SRCSLC13A5 | |
| SCHEMBL747958 | 0.89 | TP53 (0.38) | SRCSLC13A5HIF1ALMNAMAPT | |
| SCHEMBL750133 | 0.88 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5HIF1A | |
| SCHEMBL750950 | 0.88 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5HIF1A | |
| SCHEMBL748197 | 0.88 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5HIF1A | |
| SCHEMBL749647 | 0.88 | LMNA (0.39) | LMNAMAPTALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |