Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750906 | 0.94 | TP53 (0.39) | HDAC1HDAC6SRCSLC13A5PTGDR2 | |
| SCHEMBL747722 | 0.94 | ESRRG (0.41) | HDAC1HDAC6SRCSLC13A5BCHE | |
| SCHEMBL749993 | 0.93 | LPAR1 (0.39) | HDAC1HDAC6SRCSLC13A5LPAR1 | |
| SCHEMBL751065 | 0.93 | SRC (0.38) | HDAC1HDAC6SRCSLC13A5PTGDR2 | |
| SCHEMBL750133 | 0.91 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5SIGMAR1 | |
| SCHEMBL746738 | 0.90 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5LPAR1 | |
| SCHEMBL747958 | 0.90 | TP53 (0.38) | SRCSLC13A5TMEM97SIGMAR1LPAR1 | |
| SCHEMBL749647 | 0.89 | LMNA (0.39) | TMEM97SIGMAR1RAB9ANPC1MEN1 | |
| SCHEMBL750950 | 0.89 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5TMEM97 | |
| SCHEMBL748197 | 0.89 | SRC (0.36) | HDAC1HDAC6SRCSLC13A5TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |