Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954330 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1HPGDKMT2ACCKBR | |
| SCHEMBL16847591 | 0.86 | CTSL (0.62) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL18649575 | 0.85 | CNR2 (0.48) | ALDH1A1MEN1HPGDKMT2ACCKBR | |
| SCHEMBL749652 | 0.85 | SIRT2 (0.49) | ALDH1A1MEN1HPGDKMT2ACTSL | |
| SCHEMBL2300340 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1HPGDKMT2ACCKBR | |
| SCHEMBL7293004 | 0.84 | CTSK (0.51) | ALDH1A1MEN1KMT2ACTSLCTSS | |
| SCHEMBL13970298 | 0.84 | CTSK (0.51) | ALDH1A1MEN1KMT2ACTSLCTSS | |
| SCHEMBL4961276 | 0.84 | CTSK (0.57) | ALDH1A1MEN1KMT2ACTSLCTSS | |
| SCHEMBL13058656 | 0.84 | CTSK (0.57) | ALDH1A1MEN1KMT2ACTSLCTSS | |
| SCHEMBL8219708 | 0.84 | JAK3 (0.58) | CCKBRCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |