Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 14/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.42 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 4/20 | 0.37 |
| ▸ | PDE1A | P54750 | 4/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864692 | 0.85 | SLC16A1 (0.56) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL5864889 | 0.82 | SLC16A1 (0.42) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL5864831 | 0.81 | SLC16A1 (0.58) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL7007036 | 0.81 | SLC16A1 (0.57) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL7006986 | 0.81 | SLC16A1 (0.43) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL5865214 | 0.81 | ALDH1A1 (0.45) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL5864895 | 0.80 | PDE3B (0.47) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL8162346 | 0.80 | SLC16A1 (0.44) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL7008583 | 0.78 | TBXAS1 (0.42) | SLC16A1CYP2C9CYP3A4MAPKAPK2CAMK2B | |
| SCHEMBL7011267 | 0.77 | PDE1B (0.39) | SLC16A1CYP2C9CYP3A4SLC16A7PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991653-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-10-16 | — | — | EP | claimed |