SCHEMBL7499862

SCHEMBL7499862

NC(=O)OCCc1csc2cncn12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.33
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8041425 0.86 LMNA (0.33) TBXAS1LMNA
SCHEMBL7501735 0.74 RECQL (0.38) TBXAS1
SCHEMBL8052737 0.74 ALDH1A1 (0.33) TBXAS1
SCHEMBL29025283 0.72 GLA (0.39) LMNAGLA
SCHEMBL7497261 0.70 TBXAS1 (0.39) TBXAS1
SCHEMBL7496162 0.69 CYP3A4 (0.34) LMNA
SCHEMBL7503652 0.68
SCHEMBL17080164 0.68 PARP15 (0.47) LMNAGLA
SCHEMBL4791511 0.62 LMNA (0.44) LMNAGLA
SCHEMBL30698005 0.61 LMNA (0.40) LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760370-B1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA CO (JP) 2002-08-07 EP disclosed
US-5990101-A Carbapenem derivatives MEIJI SEIKA KABUSHIKI KAISHA (JP) 1999-11-23 US disclosed
EP-0760370-A1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-03-05 EP disclosed