Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 8/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 3/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550261 | 0.78 | IDO1 (0.31) | TBXAS1 | |
| SCHEMBL6893584 | 0.75 | TBXAS1 (0.32) | TBXAS1 | |
| SCHEMBL7496162 | 0.72 | CYP3A4 (0.34) | — | |
| SCHEMBL8052737 | 0.72 | ALDH1A1 (0.33) | TBXAS1 | |
| SCHEMBL8041425 | 0.72 | LMNA (0.33) | TBXAS1 | |
| SCHEMBL7500293 | 0.71 | ADH1B (0.30) | — | |
| SCHEMBL7496497 | 0.70 | TBXAS1 (0.30) | TBXAS1 | |
| SCHEMBL7499862 | 0.70 | TBXAS1 (0.33) | TBXAS1 | |
| SCHEMBL8053782 | 0.69 | KDM4E (0.38) | KDM4EHDAC6MAPK1 | |
| SCHEMBL7498371 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760370-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5990101-A | Carbapenem derivatives | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0760370-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-03-05 | — | — | EP | disclosed |