Sugi Predict

Sugi Predict / Compounds / SCHEMBL7500472

SCHEMBL7500472

SCHEMBL7500472

NNC(C(=O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSD P07339 1/20 0.52
▸ CYP2D6 P10635 1/20 0.50
▸ SRC P12931 1/20 0.50
▸ LMNA P02545 2/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ AOC3 Q16853 1/20 0.47
▸ FPR2 P25090 1/20 0.46
▸ NAALAD2 Q9Y3Q0 1/20 0.45
▸ HDAC3 O15379 1/20 0.43
▸ HDAC4 P56524 1/20 0.43
▸ HDAC1 Q13547 1/20 0.43
▸ HDAC7 Q8WUI4 1/20 0.43
▸ HDAC2 Q92769 1/20 0.43
▸ HDAC10 Q969S8 1/20 0.43
▸ HDAC11 Q96DB2 1/20 0.43
▸ HDAC8 Q9BY41 1/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11275428 1.00 CTSD (0.52) CTSDCYP2D6SRCLMNAMAPK1
Hydrochloric Acid SCHEMBL11163708 0.98 CTSD (0.50) CTSDCYP2D6SRCLMNAMAPK1
Hydrochloric Acid SCHEMBL11794945 0.98 CTSD (0.50) CTSDCYP2D6SRCLMNAMAPK1
Benzoic Acid SCHEMBL4941619 0.89 DAO (0.50) CTSDCYP2D6SRCLMNAMAPK1
SCHEMBL31023924 0.84 CTSD (0.50) CTSDCYP2D6SRCLMNAMAPK1
SCHEMBL18539179 0.84 CTSD (0.50) CTSDCYP2D6SRCLMNAMAPK1
SCHEMBL23593786 0.84 KMT2A (0.60) CTSDCYP2D6LMNAKMT2A
SCHEMBL23861285 0.81 TDP1 (0.55) CTSDCYP2D6SRCLMNAMAPK1
Hydrochloric Acid SCHEMBL11117576 0.81 CTSD (0.47) CTSDCYP2D6SRCLMNAMAPK1
SCHEMBL20581540 0.79 SRC (0.52) CTSDCYP2D6SRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117956878-A Perovskite layer manufacturing method, perovskite battery, battery assembly and photovoltaic system 浙江爱旭太阳能科技有限公司 2024-04-30 — — CN claimed
CN-109897001-A A kind of ester type compound, preparation method and application replacing diazanyl containing two 南京农业大学 2019-06-18 — — CN claimed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
CN-117956878-A Perovskite layer manufacturing method, perovskite battery, battery assembly and photovoltaic system 浙江爱旭太阳能科技有限公司 2024-04-30 — — CN disclosed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 — — US disclosed
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-29 — — US disclosed
US-11440881-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-13 — — US disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-113924290-A Thiohydrazinocarboxylic acid esters and their use 范因斯坦医学研究院 2022-01-11 — — CN disclosed
US-20200354318-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2020-11-12 — — US disclosed
WO-2020227592-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2020-11-12 — — WO disclosed
EP-1171122-A4 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO INC (US) 2002-05-29 — — EP disclosed
EP-1171122-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Merck & Co., Inc. (US) 2002-01-16 — — EP disclosed
US-6248755-B1 ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES MERCK & CO., INC. 2001-06-19 — — US disclosed
WO-2000059502-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 — — WO disclosed
US-4239901-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-12-16 — — US disclosed
US-3998950-A BACTERICIDE ISF S.P.A. (IT) 1976-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440881-B2 Thiosemicarbazates and uses thereof TST, ABAT, AADAC CTSD 1745/4885CYP2D6 2265/4885SRC 3835/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 CTSD 2491/4885CYP2D6 1386/4885SRC 4192/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC CTSD 1745/4885CYP2D6 2265/4885SRC 3835/4885
US-20200354318-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC CTSD 1745/4885CYP2D6 2265/4885SRC 3835/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT CTSD 3207/4885CYP2D6 625/4885SRC 2135/4885
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC CTSD 1745/4885CYP2D6 2265/4885SRC 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.