Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536909 | 0.72 | MAOA (0.44) | MAOAMAOBTRPA1SRD5A2MTNR1A | |
| Hydrochloric Acid SCHEMBL8742564 | 0.71 | MAOA (0.42) | MAOAMAOBTRPA1POLBSRD5A2 | |
| SCHEMBL6997599 | 0.71 | TRPA1 (0.46) | MAOAMAOBTRPA1 | |
| SCHEMBL1067727 | 0.68 | MAOA (0.59) | MAOAMAOBTRPA1SRD5A2MTNR1A | |
| SCHEMBL29906826 | 0.68 | MAOA (0.59) | MAOAMAOBTRPA1SRD5A2MTNR1A | |
| SCHEMBL3707900 | 0.67 | TRPA1 (0.46) | MAOAMAOBTRPA1 | |
| SCHEMBL29697828 | 0.67 | TRPA1 (0.44) | MAOAMAOBTRPA1POLBSRD5A2 | |
| SCHEMBL515808 | 0.67 | TRPA1 (0.44) | MAOAMAOBTRPA1POLBSRD5A2 | |
| SCHEMBL7000747 | 0.67 | TRPA1 (0.42) | TRPA1 | |
| Trifluoroacetic Acid SCHEMBL8881145 | 0.66 | MAOA (0.38) | MAOAMAOBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |