Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505001 | 0.89 | MEN1 (0.53) | ADORA1ADORA3ADORA2AADORA2BMEN1 | |
| SCHEMBL7502465 | 0.86 | PTGS2 (0.49) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL7496148 | 0.83 | CYP1A2 (0.51) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7499394 | 0.77 | PDE4B (0.50) | KDM4EALDH1A1HPGD | |
| SCHEMBL7227674 | 0.76 | ADORA3 (0.58) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL13309908 | 0.76 | ALDH1A1 (0.66) | ADORA1ADORA3ADORA2AADORA2BALDH1A1 | |
| SCHEMBL7498883 | 0.75 | SMN1; SMN2 (0.42) | KDM4EALDH1A1HPGD | |
| SCHEMBL7499282 | 0.75 | PDE4B (0.56) | ADORA3KDM4EALDH1A1HPGD | |
| SCHEMBL7504132 | 0.74 | TSHR (0.41) | KDM4EALDH1A1HPGD | |
| SCHEMBL13309909 | 0.73 | TLR8 (0.74) | ADORA1ADORA3ADORA2AADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | claimed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | claimed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | claimed |
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |