Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518511 | 0.81 | LMNA (0.36) | CYP1A2KDM4EMAPTHSD17B10SAE1 | |
| SCHEMBL7097302 | 0.75 | LMNA (0.36) | CYP1A2MAPTALDH1A1GAANPC1 | |
| SCHEMBL7510038 | 0.73 | SMPD1 (0.46) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL444734 | 0.69 | MAPT (0.42) | CYP1A2KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL1439154 | 0.67 | HSD17B10 (0.42) | CYP1A2KDM4EMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL30834651 | 0.67 | KMT2A (0.37) | CYP1A2KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20294973 | 0.67 | KMT2A (0.37) | CYP1A2KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9844093 | 0.67 | TMPRSS15 (0.47) | CYP1A2MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4698064 | 0.64 | L3MBTL1 (0.42) | CYP1A2KDM4EMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL7895429 | 0.64 | L3MBTL1 (0.47) | CYP1A2KDM4EMAPTHSD17B10SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214316-A1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016131-A2 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD (CH) | 2001-03-08 | — | — | WO | disclosed |