SCHEMBL9844093

SCHEMBL9844093

COC(=O)Oc1cc(C)on1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TMPRSS15 P98073 1/20 0.47
RAB9A P51151 8/20 0.45
NPC1 O15118 7/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
ALDH1A1 P00352 4/20 0.42
TP53 P04637 2/20 0.42
GLA P06280 1/20 0.42
EGFR P00533 1/20 0.41
GAA P10253 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875579 0.81 TMPRSS15 (0.49) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL27361867 0.81 RAB9A (0.49) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL6632393 0.79 TMPRSS15 (0.55) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL8305554 0.79 TMPRSS15 (0.48) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL23723952 0.77 TMPRSS15 (0.47) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL19520914 0.76 TMPRSS15 (0.49) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL27952188 0.75 TMPRSS15 (0.45) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL29138450 0.74 SMN1; SMN2 (0.47) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL6607334 0.73
Phosphonic Acid SCHEMBL8116540 0.72 RAB9A (0.43) TMPRSS15RAB9ANPC1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459244-A1 Sulphonilised carboxylic acid amides BAYER AG (DE) 1991-12-04 EP disclosed