Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816300 | 0.81 | BRD4 (0.45) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7519206 | 0.81 | TAS1R3 (0.48) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8816554 | 0.80 | KCNA3 (0.47) | ALDH1A1TP53KMT2AKCNA3 | |
| SCHEMBL8817468 | 0.77 | KMT2A (0.52) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7512868 | 0.75 | TAS1R3 (0.56) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8814366 | 0.74 | CYP19A1 (0.44) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL7375499 | 0.73 | MTTP (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7512604 | 0.72 | KCNA3 (0.45) | ALDH1A1TP53TAS1R3TAS1R1KMT2A | |
| SCHEMBL8813752 | 0.71 | KCNMA1 (0.49) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7342694 | 0.70 | MYC (0.68) | MAPTKDM4EALDH1A1TSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |