Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515962 | 0.97 | L3MBTL3 (0.35) | L3MBTL3L3MBTL1NPC1RAB9AUSP2 | |
| SCHEMBL7512824 | 0.96 | L3MBTL3 (0.35) | L3MBTL3L3MBTL1NPC1RAB9A | |
| SCHEMBL7512987 | 0.85 | CNR1 (0.33) | — | |
| SCHEMBL7550546 | 0.85 | HTR2A (0.33) | — | |
| SCHEMBL7554137 | 0.84 | KDM4E (0.31) | — | |
| SCHEMBL7514910 | 0.84 | CHRNB4 (0.33) | — | |
| SCHEMBL7518500 | 0.82 | ALDH1A1 (0.31) | L3MBTL3L3MBTL1 | |
| SCHEMBL7510363 | 0.82 | CNR1 (0.41) | — | |
| SCHEMBL7827664 | 0.81 | ROCK2 (0.38) | — | |
| SCHEMBL7510864 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |