Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435308 | 0.96 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL5252487 | 0.96 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL9001972 | 0.86 | TDP1 (0.40) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7598191 | 0.83 | SLC7A5 (0.44) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL29588115 | 0.82 | CYP1A2 (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7596061 | 0.82 | CYP1A2 (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7514789 | 0.81 | ALOX15 (0.41) | ALOX15TSHR | |
| SCHEMBL16268136 | 0.81 | HIF1A (0.49) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL13814004 | 0.81 | TDP1 (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7630147 | 0.80 | SLC7A5 (0.39) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170021-A2 | Conjugates of peptides and lanthanid-chelates for fluorescencediagnostic | Shering Aktiengesellschaft (DE) | 2002-01-09 | — | — | EP | disclosed |