Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572714 | 0.85 | — | — | |
| SCHEMBL15382623 | 0.82 | CYP1B1 (0.33) | TDP1CYP1A1CYP1B1TSHR | |
| SCHEMBL15782679 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TDP1CYP1A2MAPK1HSD17B10 | |
| SCHEMBL14342858 | 0.80 | MGLL (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2MMP8 | |
| SCHEMBL809342 | 0.78 | TDP1 (0.54) | ALDH1A1PTPN1PTPN11TDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2382822 | 0.76 | TDP1 (0.52) | ALDH1A1PTPN1PTPN11TDP1CYP1A2 | |
| SCHEMBL10882237 | 0.76 | LTA4H (0.50) | ALDH1A1SMN1; SMN2HTTMMP8MMP14 | |
| SCHEMBL16946575 | 0.73 | MAPK13 (0.60) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22062132 | 0.71 | CYP1B1 (0.69) | ALDH1A1PTPN1PTPN11TDP1MAPK1 | |
| SCHEMBL428698 | 0.71 | ALDH1A1 (0.71) | ALDH1A1PTPN1PTPN11TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-28 | — | — | US | disclosed |
| US-9227917-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-05 | — | — | US | disclosed |
| EP-1165526-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000061567-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZINES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| US-5990310-A | REACTING A PHENYLAZOANILINE WITH A CYANURIC HALIDE AND REDUCING THE PHENYLAZOPHENYLAMINO-S-TRIAZINE TO PRODUCE AN AMINOANILINO-S-TRIAZINE FOLLOWED BY ALKYLATION; OZONE RESISTANCE; ANTISOILANTS; DISCOLORATION INHIBITION | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| US-4667869-A | MIXTURE OF FUSIBLE SOLDER INSERT, FLUX AND THERMOCHROMIC MATERIAL | RAYCHEM CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | ALDH1A1 872/4885PTPN1 2025/4885PTPN11 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.