SCHEMBL3358667

SCHEMBL3358667

CCCCCC1(c2ccccc2C=O)CCC(C(=O)O)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
KCNH2 Q12809 1/20 0.34
S1PR5 Q9H228 3/20 0.34
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
USP2 O75604 1/20 0.33
S1PR1 P21453 3/20 0.33
S1PR3 Q99500 3/20 0.33
S1PR4 O95977 2/20 0.33
CETP P11597 3/20 0.32
CYSLTR2 Q9NS75 1/20 0.32
CYSLTR1 Q9Y271 1/20 0.32
ABL1 P00519 1/20 0.32
RIN1 Q13671 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7511121 0.83 HSD11B1 (0.39) MEN1POLBKMT2AKCNH2S1PR5
SCHEMBL8725831 0.82 CYSLTR2 (0.43) S1PR5S1PR1S1PR3S1PR4CYSLTR2
SCHEMBL7507861 0.82 S1PR1 (0.38) MEN1POLBKMT2AKCNH2S1PR5
SCHEMBL9189040 0.81 CYSLTR2 (0.44) S1PR5S1PR1S1PR3S1PR4CYSLTR2
SCHEMBL7514436 0.81 HTT (0.43) MEN1KMT2A
SCHEMBL7513588 0.80 CASP1 (0.41) MEN1POLBKMT2AKCNH2S1PR5
SCHEMBL11232446 0.80 TSHR (0.38) MEN1POLBKMT2AKCNH2S1PR5
SCHEMBL8044997 0.80 L3MBTL1 (0.39) MEN1POLBKMT2AS1PR5S1PR1
SCHEMBL7511978 0.79 PDE4B (0.40) MEN1KMT2AS1PR5S1PR1S1PR3
SCHEMBL8562488 0.79 HSD11B1 (0.39) MEN1POLBKMT2AKCNH2S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
EP-2152660-B1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2016-05-11 EP disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 MEN1 2579/4885POLB 794/4885KMT2A 770/4885
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 MEN1 2579/4885POLB 794/4885KMT2A 770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.