Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513764 | 0.84 | CYP3A4 (0.42) | NPSR1CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL3289417 | 0.76 | CYP3A4 (0.42) | NPSR1MEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL7517268 | 0.72 | POLB (0.41) | NPSR1CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL7524782 | 0.72 | POLB (0.41) | NPSR1CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL11387205 | 0.71 | KMT2A (0.37) | CYP2C9CYP2C19MEN1KMT2ACYP3A4 | |
| SCHEMBL11385622 | 0.71 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL29130447 | 0.70 | ALOX15 (0.41) | NPSR1KMT2ACYP3A4ALOX15HSP90AA1 | |
| SCHEMBL4087910 | 0.70 | MMP2 (0.38) | MMP2MMP3MMP9GRM2 | |
| SCHEMBL29130441 | 0.70 | CASP6 (0.45) | NPSR1CYP2C9CYP2C19KMT2ACYP3A4 | |
| SCHEMBL11590452 | 0.68 | PGR (0.46) | TDP1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |