SCHEMBL75150

SCHEMBL75150

C=C(C)C(=O)OCCCC(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13486939 0.95 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL75247 0.89 THRB (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL13240555 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15801130 0.86 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12416078 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28255973 0.84 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6849323 0.84 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL13265878 0.83 TSHR (0.33) TSHR
SCHEMBL28254642 0.82 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL26287228 0.82 ALDH1A1 (0.48) TSHRHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7135595-B2 Photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-11-14 US claimed
US-7014980-B2 Includes a polymer containing at least one of the following monomers: 1,1,1-trifluoro-2-trifluoromethyl-2-hydroxy-(4 or 5)-pentyl (meth)acrylate or 2-{[5-(1',1',1'-trifluoro-2'-trifluoromethyl-2'-hydroxy)propyl]norbornyl]}(meth)acrylate INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-03-21 US claimed
US-20050019696-A1 Photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-01-27 US claimed
US-6806026-B2 POLYMER OF A FLUORINATED HYDROXYALKYL ACRYLATE INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-10-19 US claimed
US-20030224283-A1 Photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-12-04 US claimed
WO-2024127808-A1 RADIATION-SENSITIVE COMPOSITION AND METHOD FOR FORMING RESIST PATTERN JSR株式会社 2024-06-20 WO disclosed
US-11786160-B2 Bio-electrode composition, bio-electrode, and method for manufacturing bio-electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-17 US disclosed
US-20230159766-A1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-11656548-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, mask blank with resist film, method for producing photomask, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
US-11357970-B2 Biomedical electrode composition, biomedical electrode and method for manufacturing the biomedical electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-14 US disclosed
US-11208509-B2 Polymer compound for conductive polymer and method for producing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-28 US disclosed
US-10851188-B2 Polymer compound for conductive polymer and method for producing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-12-01 US disclosed
US-7135595-B2 Photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-11-14 US disclosed
US-20060128914-A1 photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-06-15 US disclosed
US-7014980-B2 Includes a polymer containing at least one of the following monomers: 1,1,1-trifluoro-2-trifluoromethyl-2-hydroxy-(4 or 5)-pentyl (meth)acrylate or 2-{[5-(1',1',1'-trifluoro-2'-trifluoromethyl-2'-hydroxy)propyl]norbornyl]}(meth)acrylate INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-03-21 US disclosed
US-20050124827-A1 Precursors to fluoroalkanol-containing olefin monomers and associated methods of synthesis and use GLOBALFOUNDRIES U.S. INC. 2005-06-09 US disclosed
US-20050124828-A1 Precursors to fluoroalkanol-containing olefin monomers, and associated methods of synthesis and use GLOBALFOUNDRIES U.S. INC. 2005-06-09 US disclosed
US-20050019696-A1 Photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-01-27 US disclosed
US-6806026-B2 POLYMER OF A FLUORINATED HYDROXYALKYL ACRYLATE INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-10-19 US disclosed
US-20030224283-A1 Photoresist composition INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124827-A1 Precursors to fluoroalkanol-containing olefin monomers and associated methods of synthesis and use FASN, ELOVL1, PFAS TSHR 4455/4885THRB 2951/4885POLB 641/4885
US-20050124828-A1 Precursors to fluoroalkanol-containing olefin monomers, and associated methods of synthesis and use PFAS, FASN, ELOVL1 TSHR 4200/4885THRB 2803/4885POLB 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.