Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 9/20 | 0.60 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516176 | 1.00 | CAPN1 (0.60) | CAPN1PSMB5CTSKCTSLCTSB | |
| SCHEMBL7518132 | 0.91 | CAPN1 (0.57) | CAPN1PSMB5CTSKCTSLCTSB | |
| SCHEMBL7518851 | 0.88 | PSMB5 (0.48) | CAPN1PSMB5CTSKCTSLCTSB | |
| SCHEMBL7514127 | 0.88 | PSMB5 (0.48) | CAPN1PSMB5CTSKCTSLCTSB | |
| SCHEMBL7517851 | 0.84 | CTSK (0.63) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7514607 | 0.80 | CAPN1 (0.49) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7517814 | 0.78 | CAPN1 (0.43) | CAPN1PSMB5CTSKCTSLCTSB | |
| SCHEMBL4968070 | 0.75 | CAPN1 (1.00) | CAPN1PSMB5GAA | |
| SCHEMBL8810051 | 0.74 | CAPN1 (0.66) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7515061 | 0.72 | CTSK (0.59) | CAPN1CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | claimed |