Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517851 | 0.87 | CTSK (0.63) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7510915 | 0.87 | CAPN1 (0.46) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7514760 | 0.83 | CAPN1 (0.49) | CAPN1CCR1 | |
| SCHEMBL7518132 | 0.82 | CAPN1 (0.57) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7516176 | 0.80 | CAPN1 (0.60) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7516164 | 0.80 | CAPN1 (0.60) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7514977 | 0.77 | CAPN1 (0.59) | CAPN1ALDH1A1 | |
| SCHEMBL8812573 | 0.76 | CTSK (0.60) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL8812581 | 0.76 | CTSK (0.60) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7515061 | 0.75 | CTSK (0.59) | CAPN1CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | disclosed |