Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684924 | 0.82 | THRB (0.34) | CASP1ALOX15HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL7865964 | 0.82 | THRB (0.34) | CASP1ALOX15HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL17774719 | 0.81 | CA1 (0.41) | CA1CA2PDE10APRKCIKDM4E | |
| SCHEMBL18826532 | 0.77 | CA1 (0.48) | CA1CA2PDE10APRKCIKDM4E | |
| SCHEMBL16619563 | 0.77 | CA3 (0.39) | TRPA1ESR2XDH | |
| SCHEMBL11874166 | 0.77 | XDH (0.33) | KDM4EHSD17B10CYP3A4TDP1RECQL | |
| SCHEMBL3194749 | 0.74 | PDE10A (0.50) | CA1CA2PDE10APRKCIKDM4E | |
| SCHEMBL17774757 | 0.73 | PRKCI (0.39) | CA1CA2PDE10APRKCIKDM4E | |
| Hydrochloric Acid SCHEMBL11201276 | 0.72 | CA1 (0.43) | CA1CA2PDE10APRKCIKDM4E | |
| SCHEMBL2739345 | 0.71 | PDE10A (0.52) | CA1CA2PDE10APRKCIKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182187-A1 | Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| WO-1986002829-A1 | OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-22 | — | — | WO | claimed |
| EP-1006104-B1 | P-aminophenol substitute and its use in oxidation dye formulations | CLAIROL INC (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1006104-A1 | P-aminophenol substitute and its use in oxidation dye formulations | Bristol-Myers Squibb Company (US) | 2000-06-07 | — | — | EP | disclosed |
| US-5980584-A | NONTOXIC; REPLACEMENT FOR P-AMINOPHENOL IN OXIDATIVE HAIR DYE SYSTEMS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0359618-B1 | 2-SUBSTITUTED PARA-AMINOPHENOLS AND THEIR USE IN THE COLORATION OF KERATINIC FIBRES | L'OREAL (FR) | 1993-03-17 | — | — | EP | disclosed |
| EP-0182187-A1 | Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | disclosed |
| EP-0182187-A1 | Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | disclosed |
| WO-1986002829-A1 | OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-22 | — | — | WO | disclosed |
| WO-1986002829-A1 | OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-22 | — | — | WO | disclosed |