Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361002 | 0.80 | TYR (0.43) | — | |
| SCHEMBL16619563 | 0.77 | CA3 (0.39) | XDHADRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL7516301 | 0.77 | CA1 (0.41) | XDHCYP3A4HSD17B10KDM4EMAPT | |
| SCHEMBL13562779 | 0.73 | TRPA1 (0.32) | CYP3A4HSD17B10KDM4EMAPTBLM | |
| SCHEMBL387118 | 0.73 | GABRA1 (0.48) | CYP3A4HSD17B10KDM4EMAPTAPEX1 | |
| SCHEMBL7594286 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL11789192 | 0.70 | LMNA (0.44) | CYP3A4HSD17B10ADRA2AADRA2BADRA2C | |
| SCHEMBL11405118 | 0.70 | GABRA1 (0.46) | CYP3A4HSD17B10RECQLBLMTDP1 | |
| SCHEMBL629035 | 0.68 | — | — | |
| SCHEMBL3800611 | 0.68 | G6PD (0.37) | CYP3A4HSD17B10ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |