Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | MB | P02144 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | RARG | P13631 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339755 | 0.94 | SMN1; SMN2 (0.79) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL4555020 | 0.94 | MAPT (0.72) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL9342637 | 0.88 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL19227677 | 0.88 | MAPT (0.71) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10925259 | 0.88 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL861674 | 0.87 | SMN1; SMN2 (0.84) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10924363 | 0.87 | PKM (0.72) | MAPTALDH1A1EPHX1KMT2ACA12 | |
| SCHEMBL10927228 | 0.85 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| Aniline SCHEMBL10956685 | 0.85 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| Acetanilide SCHEMBL28762299 | 0.85 | NAPRT (0.79) | MAPTALDH1A1SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079858-A | Preparation method of 5-bromoindole-2-carboxylic acid ethyl ester or 5-bromoindole-2-carboxylic acid | — | 2026-05-26 | — | — | CN | claimed |
| CN-118948844-A | Application of triazole derivative LD-18 in preparation of anti-type 2 diabetes medicine taking PPARgamma and alpha-glucosidase as targets | 邵阳学院 | 2024-11-15 | — | — | CN | claimed |
| CN-113801015-B | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2022-11-18 | — | — | CN | claimed |
| CN-113801015-A | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2021-12-17 | — | — | CN | claimed |
| CN-109082280-B | Preparation method of liquid crystal material | 宁夏中星显示材料有限公司 | 2020-07-28 | — | — | CN | claimed |
| US-20120063996-A1 | NOVEL NIMESULIDE COMPOSITIONS | ELAN PHARMA INTERNATIONAL LTD. | 2012-03-15 | — | — | US | claimed |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | US | claimed |
| US-20090312433-A1 | TREATMENT OF VR1-ANTAGONIST-INDUCED INCREASE IN BODY TEMPERATURE WITH AN ANTIPYRETIC AGENT | AMGEN INC. | 2009-12-17 | — | — | US | claimed |
| EP-1617816-B1 | NANOPARTICULATE MELOXICAN FORMULATIONS | ELAN PHARMA INT LTD (IE) | 2009-05-13 | — | — | EP | claimed |
| EP-1938803-A2 | Formulations comprising nanoparticulate meloxican | Elan Pharma International Limited (IE) | 2008-07-02 | — | — | EP | claimed |
| WO-2004082719-A1 | DISPERSIBLE PHARMACEUTICAL COMPOSITION FOR TREATMENT OF MASTITIS AND OTIC DISORDERS | PHARMACIA CORPORATION (US) | 2004-09-30 | — | — | WO | claimed |
| US-20040156872-A1 | Novel nimesulide compositions | ELAN PHARMA INTERNATIONAL LTD. | 2004-08-12 | — | — | US | claimed |
| US-20030235617-A1 | Pharmaceutical dosage form for mucosal delivery | MCNEIL-PPC, INC | 2003-12-25 | — | — | US | claimed |
| US-20030180357-A1 | Pharmaceutical tablet | MCNEIL-PPC, INC | 2003-09-25 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-0470669-B1 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1997-11-12 | — | — | EP | claimed |
| EP-0470669-A2 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1992-02-12 | — | — | EP | claimed |
| US-4643964-A | COMPOSED OF ELECTROCONDUCTIVE PARTICLES, MELTABLE COMPOUND AND HYDROPHILIC BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1987-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040156872-A1 | Novel nimesulide compositions | NIM1K, NIT2, NCL | MAPT 244/4885ALDH1A1 3888/4885SMN1; SMN2 136/4885 |
| US-20030180357-A1 | Pharmaceutical tablet | GYPA, SORD, SRI | MAPT 953/4885ALDH1A1 1900/4885SMN1; SMN2 2397/4885 |
| US-20120063996-A1 | NOVEL NIMESULIDE COMPOSITIONS | NIM1K, NIT2, NCL | MAPT 244/4885ALDH1A1 3888/4885SMN1; SMN2 136/4885 |
| US-20090312433-A1 | TREATMENT OF VR1-ANTAGONIST-INDUCED INCREASE IN BODY TEMPERATURE WITH AN ANTIPYRETIC AGENT | VRK1, VIPR1, AVPR1A | MAPT 4532/4885ALDH1A1 983/4885SMN1; SMN2 3787/4885 |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | NOS2, NOS1, NOS3 | MAPT 4304/4885ALDH1A1 204/4885SMN1; SMN2 2638/4885 |
| US-20030235617-A1 | Pharmaceutical dosage form for mucosal delivery | SI, UGGT1, GYPA | MAPT 2192/4885ALDH1A1 1722/4885SMN1; SMN2 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.