Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 4/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879040 | 0.84 | MAPT (0.38) | RXRARXRBRXRGSRD5A2RARB | |
| SCHEMBL16952040 | 0.82 | EPHX2 (0.38) | RXRARXRBRXRGSRD5A2RARG | |
| SCHEMBL3279349 | 0.80 | CES2 (0.47) | RXRARXRBRXRGSRD5A2HSD17B10 | |
| SCHEMBL4282645 | 0.79 | ALDH1A1 (0.43) | TDP1MAPTKIF11CA1CA12 | |
| Water SCHEMBL28383353 | 0.79 | RXRB (0.57) | RXRARXRBRXRGSRD5A2RARB | |
| SCHEMBL398487 | 0.78 | TSHR (0.45) | SRD5A2TDP1SMN1; SMN2TP53MAPT | |
| SCHEMBL7522303 | 0.77 | TPMT (0.56) | RXRARXRBSRD5A2TDP1SMN1; SMN2 | |
| SCHEMBL166878 | 0.76 | RXRB (0.59) | RXRARXRBRXRGSRD5A2RARB | |
| SCHEMBL501957 | 0.76 | RXRB (0.64) | RXRARXRBRXRGSRD5A2RARB | |
| SCHEMBL61700 | 0.75 | GABRA1 (0.46) | RXRARXRBRXRGTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| WO-2002005616-A1 | NOVEL 6-PHENYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2002-01-24 | — | — | WO | disclosed |