Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514901 | 0.93 | MAPT (0.55) | ALDH1A1MAPTKMT2AMEN1USP2 | |
| SCHEMBL7512445 | 0.90 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL7098960 | 0.83 | TP53 (0.50) | ALDH1A1LMNATP53NPSR1 | |
| SCHEMBL7522388 | 0.83 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1USP2 | |
| SCHEMBL7518536 | 0.79 | TP53 (0.41) | ALDH1A1MAPTLMNATP53NPSR1 | |
| SCHEMBL7101292 | 0.78 | PGR (0.46) | ALDH1A1MAPTKMT2AMEN1USP2 | |
| SCHEMBL5185199 | 0.77 | LMNA (0.64) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL7101079 | 0.76 | TP53 (0.44) | ALDH1A1LMNATP53NPSR1 | |
| SCHEMBL7103879 | 0.74 | MAPT (0.50) | ALDH1A1MAPTKMT2AMEN1USP2 | |
| SCHEMBL22187298 | 0.73 | TP53 (0.61) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020127605-A1 | Bisubstituted carbocyclic cyclophilin binding compounds and their use | GUILFORD PHARMACEUTICALS, INC. | 2002-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020127605-A1 | Bisubstituted carbocyclic cyclophilin binding compounds and their use | PPIG, PIN1, PPIH | ALDH1A1 1905/4885MAPT 1168/4885KMT2A 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.