Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519380 | 1.00 | LMNA (0.56) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL7775216 | 0.88 | ALDH1A1 (0.55) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL7954574 | 0.88 | ALDH1A1 (0.55) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL7954572 | 0.88 | ALDH1A1 (0.55) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL2852865 | 0.82 | LMNA (0.53) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL18277714 | 0.82 | LMNA (0.50) | LMNAALDH1A1KDM4EGAANPC1 | |
| SCHEMBL7609219 | 0.80 | RAB9A (0.60) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL3936094 | 0.80 | RAB9A (0.60) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL7513910 | 0.80 | MAPT (0.56) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL1646935 | 0.78 | MAPT (0.67) | LMNAMAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019496-A1 | Ligands for metal affinity chromatography | PEVOW GERALD (US) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019496-A1 | Ligands for metal affinity chromatography | MLX, RBX1, BRIX1 | LMNA 2973/4885MAPT 1963/4885ALDH1A1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.