SCHEMBL75208

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11982400	0.89	MAPT (0.36)	ALDH1A1MAPTCA12GMNNCA1
	SCHEMBL20276195	0.84	ALDH1A1 (0.32)	ALDH1A1MAPTCA12GMNNCA1
	SCHEMBL74721	0.84	CHRM2 (0.33)	ALDH1A1MAPTCA12GMNNCA1
	SCHEMBL13431248	0.81	SGMS1 (0.30)	ALDH1A1MAPTCA12GMNNCA1
	SCHEMBL18714189	0.81	THRB (0.31)	—
	SCHEMBL14624482	0.81	ALDH1A1 (0.42)	ALDH1A1TSHR
	SCHEMBL18643960	0.81	NPC1 (0.30)	NPC1RAB9ANPSR1L3MBTL1
	SCHEMBL13109788	0.81	ALDH1A1 (0.42)	ALDH1A1TSHR
	SCHEMBL13125759	0.81	ALDH1A1 (0.42)	ALDH1A1TSHR
	SCHEMBL24084357	0.81	ALDH1A1 (0.53)	ALDH1A1MAPTCA12GMNNCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.