SCHEMBL74721

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL178886	0.90	MAPT (0.34)	SGMS1SGMS2CA12GMNNALDH1A1
	SCHEMBL75208	0.84	ALDH1A1 (0.32)	SGMS1SGMS2CA12GMNNALDH1A1
	SCHEMBL18714189	0.84	THRB (0.31)	—
	SCHEMBL9612194	0.84	MAPT (0.34)	CHRM2CHRM4CHRM1CHRM3SGMS1
	SCHEMBL20276195	0.82	ALDH1A1 (0.32)	SGMS1SGMS2CA12GMNNALDH1A1
	SCHEMBL76534	0.81	CHRM2 (0.35)	CHRM2CHRM4CHRM1CHRM3ALDH1A1
	SCHEMBL23963192	0.81	CHRM2 (0.32)	CHRM2CHRM4CHRM5CHRM1CHRM3
	SCHEMBL25618017	0.79	CHRM2 (0.33)	CHRM2CHRM4CHRM5CHRM1CHRM3
	SCHEMBL13109788	0.78	ALDH1A1 (0.42)	ALDH1A1
	SCHEMBL13125759	0.78	ALDH1A1 (0.42)	ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.