Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CIT | O14578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL2558877 | 0.85 | CRBN (0.50) | CRBNMAP4K4 | |
| Adenine SCHEMBL6256495 | 0.82 | ATAD2 (0.40) | SLC7A5 | |
| Valine SCHEMBL3642426 | 0.81 | CRBN (0.55) | CRBNSLC7A5CIT | |
| Adenine SCHEMBL8469554 | 0.77 | ALDH1A1 (0.43) | CRBNMAP4K4 | |
| Guanine SCHEMBL4577520 | 0.76 | KDM4E (0.43) | CRBNMAP4K4 | |
| Adenine SCHEMBL14125907 | 0.72 | PI4KA (0.39) | MAP4K4 | |
| Uracil SCHEMBL1529844 | 0.72 | CRBN (0.61) | CRBN | |
| Adenine SCHEMBL6227731 | 0.71 | ATAD2 (0.37) | CRBNMAP4K4 | |
| Adenine SCHEMBL1577865 | 0.71 | SLC7A5 (0.47) | SLC7A5CIT | |
| Guanine SCHEMBL2636585 | 0.71 | KDM4E (0.38) | CRBNMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246847-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | Synaptic Pharmaceutical Corporation (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2002002744-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-1032423-A1 | DNA ENCODING MAMMALIAN NEUROPEPTIDE FF (NPFF) RECEPTORS AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-2000018438-A1 | DNA ENCODING MAMMALIAN NEUROPEPTIDE FF (NPFF) RECEPTORS AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-04-06 | — | — | WO | disclosed |
| WO-1999029887-A1 | DNA ENCODING A MAMMALIAN LPA RECEPTOR AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1999-06-17 | — | — | WO | disclosed |