Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525831 | 0.82 | MTNR1A (0.46) | MTNR1AHPGDALDH1A1 | |
| SCHEMBL10598218 | 0.79 | SNCA (0.39) | HPGDMAPTCYP2C9ALDH1A1GAA | |
| SCHEMBL10596213 | 0.73 | ALDH1A1 (0.41) | HPGDMAPTCYP2C9ALDH1A1GAA | |
| SCHEMBL8482119 | 0.73 | MTNR1A (0.49) | MTNR1AHPGDMAPTALDH1A1PKM | |
| SCHEMBL28542745 | 0.72 | CA2 (0.45) | MAPTALDH1A1GAA | |
| SCHEMBL4620923 | 0.72 | S1PR3 (0.43) | HPGDMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2058018 | 0.72 | ALDH1A1 (0.35) | HPGDMAPTALDH1A1GAA | |
| SCHEMBL10652394 | 0.71 | S1PR3 (0.45) | HPGDMAPTCYP3A4ALDH1A1GAA | |
| SCHEMBL6259776 | 0.71 | S1PR3 (0.36) | HPGDMAPTCYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL16028578 | 0.71 | CA2 (0.42) | MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |