Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521265 | 0.82 | MTNR1A (0.53) | MTNR1AHPGDALDH1A1 | |
| SCHEMBL10598218 | 0.80 | SNCA (0.39) | SNCAHPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL10596213 | 0.74 | ALDH1A1 (0.41) | SNCAHPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL4620923 | 0.73 | S1PR3 (0.43) | SNCAHPGDALDH1A1HSD17B10CA12 | |
| SCHEMBL28542745 | 0.73 | CA2 (0.45) | SNCAALDH1A1HSD17B10TDP1CA2 | |
| SCHEMBL2058018 | 0.72 | ALDH1A1 (0.35) | SNCAHPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL7525829 | 0.72 | HTT (0.33) | MTNR1A | |
| SCHEMBL10652394 | 0.72 | S1PR3 (0.45) | HPGDALDH1A1TSHRTDP1CA12 | |
| SCHEMBL6259776 | 0.72 | S1PR3 (0.36) | SNCAHPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL600326 | 0.72 | TAAR1 (0.36) | SNCAHPGDALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |