Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | CTSS | P25774 | 1/20 | 0.67 |
| ▸ | CTSK | P43235 | 1/20 | 0.67 |
| ▸ | NMBR | P28336 | 5/20 | 0.62 |
| ▸ | TACR3 | P29371 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833490 | 0.90 | CTSL (0.76) | CTSLCTSSCTSKNMBRTACR3 | |
| SCHEMBL15145404 | 0.85 | CTSL (0.77) | CTSLCTSSCTSKNMBRTACR3 | |
| SCHEMBL15145364 | 0.85 | CTSL (0.77) | CTSLCTSSCTSKNMBRTACR3 | |
| SCHEMBL7522969 | 0.84 | CTSS (0.56) | CTSLCTSSCTSKMAPTCA2 | |
| SCHEMBL18879584 | 0.83 | CTSL (0.74) | CTSLCTSSCTSKNMBRTACR3 | |
| SCHEMBL17884340 | 0.83 | CTSL (0.74) | CTSLCTSSCTSKNMBRTACR3 | |
| SCHEMBL9834534 | 0.83 | CTSL (0.80) | CTSLCTSSCTSKNMBRMAPT | |
| SCHEMBL17807348 | 0.83 | CTSL (0.80) | CTSLCTSSCTSKNMBRTACR3 | |
| SCHEMBL7519424 | 0.82 | BRS3 (0.59) | CTSLNMBRTACR1CA2KMT2A | |
| SCHEMBL7443477 | 0.82 | CTSL (0.72) | CTSLCTSSCTSKNMBRTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |