Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522328 | 1.00 | MAPT (0.43) | MAPTRAB9ANPC1KDM4EJUN | |
| SCHEMBL7118884 | 0.92 | MAPK1 (0.37) | MAPTRAB9ANPC1KDM4EJUN | |
| SCHEMBL7522228 | 0.85 | JUN (0.38) | MAPTRAB9ANPC1KDM4EJUN | |
| SCHEMBL7054847 | 0.85 | JUN (0.38) | MAPTRAB9ANPC1KDM4EJUN | |
| SCHEMBL7052644 | 0.84 | MEN1 (0.40) | MAPTNPC1LMNATDP1L3MBTL1 | |
| SCHEMBL7052640 | 0.84 | MEN1 (0.40) | MAPTNPC1LMNATDP1L3MBTL1 | |
| SCHEMBL7052809 | 0.76 | CYP11B1 (0.46) | MAPTRAB9ANPC1KDM4EJUN | |
| SCHEMBL7523335 | 0.76 | CYP11B1 (0.46) | MAPTRAB9ANPC1KDM4EJUN | |
| SCHEMBL7529301 | 0.73 | ALDH1A1 (0.46) | MAPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL17787987 | 0.70 | RAB9A (0.56) | MAPTRAB9ANPC1KDM4EJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | disclosed |