Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528241 | 0.93 | PKM (0.43) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL7528615 | 0.82 | MEN1 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL8906827 | 0.82 | ALDH1A1 (0.38) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL7528572 | 0.79 | FLT3 (0.35) | KDM4EKMT2A | |
| SCHEMBL7532149 | 0.78 | HPGD (0.46) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL7523494 | 0.76 | LMNA (0.49) | PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL7526174 | 0.76 | PKM (0.32) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL708587 | 0.76 | ALDH1A1 (0.42) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL14435485 | 0.74 | SMN1; SMN2 (0.45) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL7529664 | 0.73 | PKM (0.39) | PKMALDH1A1SMN1; SMN2HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |