SCHEMBL7523671

SCHEMBL7523671

CCC=C(C(=O)O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.40
GLA P06280 1/20 0.40
LMNA P02545 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2827407 0.80 GLA (0.44) HSD11B1GLALMNAKDM4EHTT
SCHEMBL2019242 0.76 THRB (0.41) HSD11B1GLALMNAKDM4EHTT
SCHEMBL595457 0.71 ALDH1A1 (0.47) HSD11B1ALDH1A1MEN1KMT2A
SCHEMBL6125488 0.71 ALDH1A1 (0.47) HSD11B1ALDH1A1MEN1KMT2A
SCHEMBL19873125 0.70 ALDH1A1 (0.40) HSD11B1GLALMNAKDM4EHTT
SCHEMBL29281849 0.70 GABBR2 (0.38) HSD11B1GLALMNAKDM4EHTT
SCHEMBL15401621 0.69 GLA (0.36) HSD11B1GLALMNAKDM4EHTT
SCHEMBL15020935 0.69 ALDH1A1 (0.40) HSD11B1GLALMNAKDM4EHTT
SCHEMBL27899350 0.68 HSD11B1 (0.46) HSD11B1GLAKDM4EHTTALDH1A1
SCHEMBL15922695 0.68 EPHX2 (0.34) HSD11B1LMNAKDM4EHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020058198-A1 Fluorinated phenolic polymers and photoresist compositions comprising same SHIPLEY COMPANY, L.L.C. 2002-05-16 US disclosed
WO-2002021212-A2 FLUORINATED PHENOLIC POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING SAME SHIPLEY COMPANY, L.L.C. (US) 2002-03-14 WO disclosed