Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14112707 | 0.82 | ALDH1A1 (0.40) | LMNAALDH1A1GAAPKMMEN1 | |
| SCHEMBL808442 | 0.72 | MEN1 (0.39) | LMNAALDH1A1GAAPKMMEN1 | |
| Bromide SCHEMBL28241411 | 0.70 | MEN1 (0.38) | LMNAALDH1A1GAAPKMMEN1 | |
| SCHEMBL8190077 | 0.70 | GAA (0.41) | ALDH1A1GAAPKMMEN1TSHR | |
| SCHEMBL10665143 | 0.70 | HSP90AA1 (0.35) | LMNAALDH1A1GAAPKMMEN1 | |
| SCHEMBL27661786 | 0.70 | MEN1 (0.38) | LMNAALDH1A1GAAPKMMEN1 | |
| SCHEMBL5773300 | 0.69 | HTR2A (0.56) | LMNAMEN1TSHRKMT2AL3MBTL1 | |
| Biphenyl SCHEMBL27574943 | 0.69 | ALDH1A1 (0.41) | LMNAALDH1A1GAATRPA1PKM | |
| SCHEMBL5771311 | 0.69 | HTR2A (0.56) | LMNAMEN1TSHRKMT2AL3MBTL1 | |
| SCHEMBL7523648 | 0.69 | GAA (0.45) | ALDH1A1GAAPKMMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872466-B1 | Process for the synthesis of 1,7-diaryl or 1,7-heteroarylheptan-4-ols and synthetic intermediates | FABBRICA ITALIANA SINTETICI SPA (IT) | 2002-01-30 | — | — | EP | disclosed |
| US-5973157-A | Process for the synthesis of 1,7-diarly or heteroaryl-heptane-4-ols and new synthetic intermediates | F.I.S. FABBRICA ILTALIANA SINTETICI S.P.A. (IT) | 1999-10-26 | — | — | US | disclosed |
| EP-0872466-A1 | Process for the synthesis of 1,7-diaryl or 1,7-heteroarylheptan-4-ols and synthetic intermediates | F.I.S. FABBRICA ITALIANA SINTETICI S.p.A. (IT) | 1998-10-21 | — | — | EP | disclosed |