Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523949 | 0.93 | — | — | |
| SCHEMBL5312005 | 0.83 | — | — | |
| SCHEMBL1837224 | 0.83 | KDM4E (0.48) | HIF1AMAOAMAOBTSHRKDM4E | |
| SCHEMBL7766501 | 0.80 | PAOX (0.48) | HIF1AMAOAMAOBTSHRKDM4E | |
| SCHEMBL14103804 | 0.80 | HIF1A (0.38) | HIF1AMAOAMAOBTSHRKDM4E | |
| SCHEMBL436282 | 0.80 | ALOX15 (0.47) | HIF1AMAOAMAOBTSHRMAPT | |
| SCHEMBL27388605 | 0.80 | ALDH1A1 (0.47) | HIF1ATSHRKDM4EMAPK1MAPT | |
| SCHEMBL1309360 | 0.80 | KDM4E (0.52) | HIF1AKDM4EMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1839119 | 0.80 | KDM4E (0.52) | HIF1AKDM4EMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11173620 | 0.80 | KDM4E (0.52) | HIF1AKDM4EMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784528-B1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING & MFG (US) | 2002-01-30 | — | — | EP | claimed |
| US-5725617-A | Abrasive articles with encapsulated lubricant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-10 | — | — | US | claimed |
| EP-0784528-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| WO-1996011085-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-18 | — | — | WO | claimed |
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | ARARIS BIOTECH AG (CH) | 2026-01-01 | — | — | US | disclosed |
| CN-113698414-B | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-110312730-B | Cytotoxins and conjugates, uses thereof and methods of preparation | 四川科伦博泰生物医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20220072141-A1 | PROTEIN-DRUG CONJUGATES COMPRISING CAMPTOTHECIN ANALOGS AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2022-03-10 | — | — | US | disclosed |
| WO-2017048728-A1 | TARGETED CONJUGATES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-23 | — | — | WO | disclosed |
| WO-2016151432-A1 | BIFUNCTIONAL CYTOTOXIC AGENTS CONTAINING THE CTI PHARMACOPHORE | PFIZER INC. (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-2015110935-A1 | BIFUNCTIONAL CYTOTOXIC AGENTS | PFIZER INC. (US) | 2015-07-30 | — | — | WO | disclosed |
| EP-0784528-B1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING & MFG (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5725617-A | Abrasive articles with encapsulated lubricant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0784528-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011085-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | NECTIN4, IGSF11, VSIG8 | HIF1A 3279/4885MAOA 4707/4885MAOB 4726/4885 |
| US-20220072141-A1 | PROTEIN-DRUG CONJUGATES COMPRISING CAMPTOTHECIN ANALOGS AND METHODS OF USE THEREOF | TGM2, QPCT, TGM3 | HIF1A 1511/4885MAOA 2766/4885MAOB 3386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.