Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911233 | 0.84 | ALOX5AP (0.38) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4910398 | 0.82 | ALDH1A1 (0.49) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4929334 | 0.74 | CCR2 (0.77) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL11458038 | 0.72 | CYP19A1 (0.54) | CYP2C9CYP2C19CYP19A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11465936 | 0.71 | LMNA (0.43) | SMN1; SMN2ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL3179011 | 0.68 | PLCG1 (0.47) | SMN1; SMN2ALDH1A1PLCG1LMNAKMT2A | |
| SCHEMBL5072430 | 0.67 | PLCG1 (0.48) | ALDH1A1PLCG1ALOX5APFEN1SLC22A12 | |
| SCHEMBL6054468 | 0.67 | ALDH1A1 (0.44) | CYP2C9CYP2C19CYP19A1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30209361 | 0.67 | PLCG1 (0.46) | SMN1; SMN2ALDH1A1PLCG1LMNAKMT2A | |
| SCHEMBL11476143 | 0.67 | RAB9A (0.49) | CYP19A1SMN1; SMN2ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198199-A1 | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2002-12-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198199-A1 | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade | TFPI, F2, PLAT | CCR2 2642/4885CYP2C9 181/4885CYP3A4 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.