Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | RORB | Q92753 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457340 | 0.95 | MAPK13 (0.49) | PBRM1ALDH1A1ADORA1MAPTGAA | |
| SCHEMBL7524261 | 0.91 | RORC (0.55) | PBRM1ALDH1A1MAPTGAAPTGDR2 | |
| SCHEMBL31377031 | 0.84 | MAPT (0.55) | ALDH1A1MAPTGAAPTGDR2RORC | |
| SCHEMBL451330 | 0.84 | MAPT (0.55) | ALDH1A1MAPTGAAPTGDR2RORC | |
| SCHEMBL3784596 | 0.82 | BCAT2 (0.63) | ALDH1A1MAPTGAAPTGDR2RORC | |
| SCHEMBL6422025 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ADORA1MAPTGAAMEN1 | |
| Hydrochloric Acid SCHEMBL6775126 | 0.82 | MAPT (0.53) | ALDH1A1MAPTGAAPTGDR2RORC | |
| SCHEMBL3138403 | 0.81 | CYP2C9 (0.53) | PBRM1ALDH1A1ADORA1MAPTGAA | |
| SCHEMBL3138405 | 0.81 | CYP2C9 (0.53) | PBRM1ALDH1A1ADORA1MAPTGAA | |
| SCHEMBL7167628 | 0.81 | MEN1 (0.66) | ALDH1A1ADORA1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |