Water

Water

SCHEMBL7524299

O.[NaH].[SiH4]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27469648 1.00
Water SCHEMBL28801943 1.00
Water SCHEMBL11784306 0.87
Water SCHEMBL28033227 0.87
Water SCHEMBL11784309 0.87
Water SCHEMBL94343 0.82
Water SCHEMBL11845423 0.82
Water SCHEMBL5802169 0.82
Water SCHEMBL8153667 0.82
Water SCHEMBL2299753 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325093-A Method for preparing raw phenyl silicone rubber by one-pot method 江西蓝星星火有机硅有限公司 2024-07-12 CN claimed
CN-105778104-B A kind of add-on type liquid fluorine silicon rubber base glue and preparation method thereof 威海新元化工有限公司 2018-08-24 CN claimed
CN-105778104-A Addition type liquid fluorinated silicone rubber base rubber and preparation method thereof 威海新元化工有限公司 2016-07-20 CN claimed
CN-104327268-A Siloxane copolymer containing ethyl phenyl silica chain links and preparation method thereof UNIV HANGZHOU NORMAL 2015-02-04 CN claimed
CN-120157122-A Method for reducing and purifying graphite alkali-melting silicon-removing sodium hydroxide 黑龙江科技大学 2025-06-17 CN disclosed
CN-118325093-A Method for preparing raw phenyl silicone rubber by one-pot method 江西蓝星星火有机硅有限公司 2024-07-12 CN disclosed
CN-114381001-B Preparation method of solvent-resistant fluorosilicone rubber with wide temperature range and composition thereof 山东华夏神舟新材料有限公司 2023-06-23 CN disclosed
CN-114381001-A Preparation method of wide-temperature-range solvent-resistant fluorosilicone rubber and composition thereof 山东华夏神舟新材料有限公司 2022-04-22 CN disclosed
CN-110156826-B Diphenyl cyclotrisiloxane and preparation method and application thereof WEIHAI NEWERA CHEMICAL CO.,LTD. (CN) 2021-08-31 CN disclosed
CN-110156826-A Diphenyl cyclotrisiloxane and the preparation method and application thereof 威海新元化工有限公司 2019-08-23 CN disclosed
CN-104761912-B A kind of damping silicon rubber with smaller temperature effect and preparation method thereof 山东大学 2017-11-07 CN disclosed
CN-107151551-A A kind of three-phase nanoemulsions with core shell structure and its preparation method and application 中国石油化工股份有限公司 2017-09-12 CN disclosed
CN-103391711-A Plant growth method and silicon-rich foliage plant TAKENAKA GARDEN AFFORESTATION INC 2013-11-13 CN disclosed
WO-2013100963-A1 PRODUCTION OF TITANIUM DIOXIDE PIGMENTS FANG ZHIGANG ZAK (US) 2013-07-04 WO disclosed
WO-2013088599-A1 PLANT GROWTH METHOD AND SILICON-RICH FOLIAGE PLANT TAKENAKA GARDEN AFFORESTATION INC. (JP) 2013-06-20 WO disclosed
CN-101837990-B Fluorine-containing all-silica MFI zeolite molecular sieve and preparation method thereof UNIV JIANGXI NORMAL 2012-08-22 CN disclosed
CN-101837990-A Fluorine-containing all-silica MFI zeolite molecular sieve and preparation method thereof UNIV JIANGXI NORMAL 2010-09-22 CN disclosed
CN-101376709-A Preparation of hydroxy end capped poly(methyl(trifluoropropyl) siloxane) UNIV HANGZHOU NORMAL (CN) 2009-03-04 CN disclosed
JP-2002020212-A METHOD FOR ACCELERATING PLANT GROWTH AND AMELIORATING STORAGE, COMPOSITION FOR ACCELERATING PLANT GROWTH AND AMELIORATING STORAGE AND METHOD FOR PRODUCING THE SAME NEL BIOTECH CO LTD 2002-01-23 JP disclosed
JP-2000245419-A FUNCTIONAL ALKALINE EARTH IONIZED FOOD ADDITIVE COMPOSITION, ITS PRODUCTION AND USING METHOD BARODON CASHPIA CORP 2000-09-12 JP disclosed