Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112029 | 0.84 | HSD17B10 (0.41) | SLC6A9KDM4ETDP1ITGB3ITGA2B | |
| SCHEMBL1197622 | 0.81 | HSD17B10 (0.42) | LTA4HSLC6A9ACEITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL1374273 | 0.73 | NPC1 (0.40) | LTA4HACEITGB3ITGA2BOGFRL1 | |
| SCHEMBL30764646 | 0.69 | NPC1 (0.35) | SLC6A9OGFRL1OPRL1 | |
| SCHEMBL8812832 | 0.67 | SIGMAR1 (0.38) | ACEITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL27487446 | 0.67 | LTA4H (0.37) | LTA4HACEITGB3ITGA2B | |
| SCHEMBL6299872 | 0.66 | CHRM5 (0.37) | ITGB3ITGA2B | |
| SCHEMBL28945745 | 0.66 | KDM4E (0.58) | LTA4HKDM4ETDP1OGFRL1OPRL1 | |
| SCHEMBL6092369 | 0.66 | KDM4E (0.58) | LTA4HKDM4ETDP1OGFRL1OPRL1 | |
| Hydrochloric Acid SCHEMBL12480511 | 0.65 | KDM4E (0.56) | LTA4HKDM4ETDP1OGFRL1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358704-A | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents | BRISTOL-MYERS SQUIBB (US) | 1994-10-25 | — | — | US | claimed |
| EP-1184377-A1 | Hepatobiliary magnetic resonance contrast agents | BRACCO International B.V. (NL) | 2002-03-06 | — | — | EP | disclosed |
| WO-1995009161-A1 | HEPATOBILIARY MAGNETIC RESONANCE CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 1995-04-06 | — | — | WO | disclosed |
| US-5358704-A | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents | BRISTOL-MYERS SQUIBB (US) | 1994-10-25 | — | — | US | disclosed |