Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524866 | 0.81 | LTA4H (0.37) | ITGB3ITGA2BSLC6A9ACELTA4H | |
| SCHEMBL9112029 | 0.79 | HSD17B10 (0.41) | HSD17B10ITGB3ITGA2BSLC6A9 | |
| SCHEMBL30764646 | 0.78 | NPC1 (0.35) | SLC6A9POLBTSHRDRD2DRD4 | |
| Tetraxetan SCHEMBL2635294 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR | |
| SCHEMBL321989 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR | |
| SCHEMBL6848102 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR | |
| Tetraxetan SCHEMBL2017956 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR | |
| SCHEMBL173508 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR | |
| Tetraxetan SCHEMBL18018 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR | |
| SCHEMBL6744121 | 0.76 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064026-A1 | Lipophilic metal complexes for necrosis and infarction imaging | SCHERING AG (DE) | 2003-04-03 | — | — | US | claimed |
| US-6495118-B1 | Lipophilic metal complexes for necrosis and infarction imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | claimed |
| US-8741262-B2 | Targeted radiotherapy | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2014-06-03 | — | — | US | disclosed |
| EP-2219683-B1 | TARGETED RADIOTHERAPY | UNIV LEUVEN KATH (BE) | 2012-05-30 | — | — | EP | disclosed |
| US-20110038795-A1 | TARGETED RADIOTHERAPY | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-02-17 | — | — | US | disclosed |
| EP-1184377-B1 | Hepatobiliary magnetic resonance contrast agents | BRACCO INT BV (NL) | 2005-02-02 | — | — | EP | disclosed |
| US-20030064026-A1 | Lipophilic metal complexes for necrosis and infarction imaging | SCHERING AG (DE) | 2003-04-03 | — | — | US | disclosed |
| EP-1017424-A1 | LIPOPHILIC METAL COMPLEXES FOR NECROSIS AND INFARCT IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999016474-A1 | LIPOPHILIC METAL COMPLEXES FOR NECROSIS AND INFARCT IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | disclosed |