SCHEMBL30764646

SCHEMBL30764646

O=C(O)CN1CCN(CC(=O)O)[C@@H]2CCCC[C@H]2N(CC(=O)O)Cc2cccc(n2)C1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
OGFRL1 Q5TC84 6/20 0.35
OPRM1 P35372 2/20 0.35
OPRD1 P41143 2/20 0.35
OPRK1 P41145 2/20 0.35
SLC6A9 P48067 1/20 0.34
OPRL1 P41146 4/20 0.34
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM1 P11229 2/20 0.33
POLB P06746 1/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9205301 0.84 EGLN1 (0.40) ALOX15SLC6A9POLB
SCHEMBL9266166 0.82 SLC6A9 (0.34) SLC6A9POLB
SCHEMBL1394889 0.82 SLC6A9 (0.42) SLC6A9POLB
SCHEMBL7869921 0.81 EGLN1 (0.39) NPC1ALOX15SLC6A9POLB
SCHEMBL16021612 0.80 SLC6A9 (0.44) SLC6A9
SCHEMBL7871400 0.80 ALDH1A1 (0.40) NPC1ALOX15POLB
SCHEMBL9024977 0.79 SIGMAR1 (0.35) SLC6A9POLBDRD2DRD4
SCHEMBL20624199 0.78 EGLN1 (0.36) SLC6A9POLB
SCHEMBL23975536 0.78 SLC6A9 (0.36) SLC6A9
SCHEMBL24201117 0.78 SLC6A9 (0.40) SLC6A9CHRM1DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041776-A1 POLYMER CONTRAST AGENT KOWA COMPANY, LTD. (JP) 2026-02-12 US disclosed
EP-4570837-A1 POLYMER CONTRAST AGENT KOWA COMPANY, LTD. (JP) 2025-06-18 EP disclosed
CN-119677788-A Polymer contrast medium 兴和株式会社 2025-03-21 CN disclosed
WO-2024034686-A1 POLYMER CONTRAST AGENT 興和株式会社 2024-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041776-A1 POLYMER CONTRAST AGENT RXFP3, HAX1, MSR1 NPC1 1418/4885LMNA 1424/4885ALOX15 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.