Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528950 | 0.86 | L3MBTL1 (0.42) | ALDH1A1CNR1CNR2CES2CES1 | |
| SCHEMBL7532764 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPK14CNR1CNR2CES2 | |
| SCHEMBL7525193 | 0.85 | CES2 (0.40) | ALDH1A1CNR1CNR2CES2CES1 | |
| SCHEMBL7529687 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPK14CNR1CNR2CES2 | |
| SCHEMBL7522596 | 0.84 | F2R (0.39) | ALDH1A1CNR1CNR2CES2CES1 | |
| SCHEMBL7523818 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK14CNR1CNR2CES2 | |
| SCHEMBL7523810 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK14CNR1CNR2CES2 | |
| SCHEMBL7523804 | 0.84 | HDAC3 (0.41) | ALDH1A1CNR1CNR2CES2CES1 | |
| SCHEMBL7527282 | 0.84 | CES2 (0.42) | ALDH1A1MAPK14CNR1CNR2CES2 | |
| SCHEMBL7522572 | 0.83 | LMNA (0.39) | ALDH1A1CNR1CNR2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184367-A1 | AMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-03-06 | — | — | EP | disclosed |