SCHEMBL7525862

SCHEMBL7525862

CCc1cc(C2CC(=O)OC2=O)c2ccccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.40
SIRT2 Q8IXJ6 5/20 0.37
PLA2G6 O60733 4/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
MAPK1 P28482 2/20 0.36
HPGD P15428 2/20 0.36
FAAH O00519 1/20 0.36
NPC1 O15118 1/20 0.36
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
MTOR P42345 1/20 0.36
RAB9A P51151 1/20 0.36
BLM P54132 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TRPC5 Q9UL62 1/20 0.36
TRPC6 Q9Y210 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993620 0.82 SIRT2 (0.47) SIRT2PLA2G6ALDH1A1MAPTMAPK1
SCHEMBL7533164 0.77 PLA2G6 (0.56) PLA2G6ALDH1A1MAPTMAPK1HPGD
SCHEMBL5951963 0.75 ACHE (0.41) HTR6ALDH1A1MAPTMAPK1NPC1
SCHEMBL7531010 0.75 ALDH1A1 (0.39) PLA2G6ALDH1A1MAPTMAPK1HPGD
SCHEMBL4255311 0.74 ALDH1A1 (0.39) SIRT2PLA2G6ALDH1A1MAPTMAPK1
SCHEMBL30772490 0.72 ALDH1A1 (0.42) SIRT2PLA2G6ALDH1A1MAPTMAPK1
SCHEMBL12664899 0.71 CTRC (0.44) ALDH1A1MAPTHPGDHSD17B10ALDH2
SCHEMBL7527580 0.70 ALDH1A1 (0.35) SIRT2PLA2G6ALDH1A1MAPTMAPK1
SCHEMBL30438970 0.70 SIRT2 (0.42) SIRT2PLA2G6ALDH1A1MAPTMAPK1
SCHEMBL7528131 0.69 MAPT (0.44) PLA2G6ALDH1A1MAPTMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725302-B1 A process of producing a polyimide block copolymer JAPAN SYNTHETIC RUBBER CO LTD (JP) 2002-04-03 EP disclosed
EP-0725302-A2 A process of producing a polyimide block copolymer JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-08-07 EP disclosed